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Mechanistic insight into Pertussis Toxin and lectin signaling using T-cells engineered to express a CD8α/CD3ζ chimeric receptor

Mammalian cell-surface receptors typically display N- or O-linked glycans added post-translationally. Plant lectins such as PHA can activate the TCR and other cell surface receptors by binding to glycans and initiating receptor cross-linking. Pathogenic microorganisms such as Bordetella pertussis al...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schneider, Olivia D., Millen, Scott H., Weiss, Alison A., Miller, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359064/
https://ncbi.nlm.nih.gov/pubmed/22551306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3002693
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