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Mechanistic insight into Pertussis Toxin and lectin signaling using T-cells engineered to express a CD8α/CD3ζ chimeric receptor
Mammalian cell-surface receptors typically display N- or O-linked glycans added post-translationally. Plant lectins such as PHA can activate the TCR and other cell surface receptors by binding to glycans and initiating receptor cross-linking. Pathogenic microorganisms such as Bordetella pertussis al...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359064/ https://ncbi.nlm.nih.gov/pubmed/22551306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3002693 |
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