Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs

BACKGROUND: Glioblastomas exhibit a high level of chemotherapeutic resistance, including to the antimitotic agents vincristine and taxol. During the mitotic agent-induced arrest, glioblastoma cells are able to perform damage-control and self-repair to continue proliferation. Monopolar spindle 1 (MPS...

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Bibliografski detalji
Glavni autori: Tannous, Bakhos A., Kerami, Mariam, Van der Stoop, Petra M., Kwiatkowski, Nicholas, Wang, Jinhua, Zhou, Wenjun, Kessler, Almuth F., Lewandrowski, Grant, Hiddingh, Lotte, Sol, Nik, Lagerweij, Tonny, Wedekind, Laurine, Niers, Johanna M., Barazas, Marco, Nilsson, R. Jonas A., Geerts, Dirk, De Witt Hamer, Philip C., Hagemann, Carsten, Vandertop, W. Peter, Van Tellingen, Olaf, Noske, David P., Gray, Nathanael S., Würdinger, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760778/
https://ncbi.nlm.nih.gov/pubmed/23940287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt168
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