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Insulin Receptor Substrate (IRS)-1 Regulates Murine Embryonic Stem (mES) Cells Self-Renewal

Mouse embryonic stem (mES) cells are pluripotent cells that can be propagated in vitro with leukemia inhibitory factor (LIF) and serum. Intracellular signaling by LIF is principally mediated by activation of STAT-3, although additional pathways for self-renewal have been described. Here, we identifi...

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Main Authors: RUBIN, RAPHAEL, ARZUMANYAN, ALLA, SOLIERA, ANGELA RACHELE, ROSS, BRIAN, PERUZZI, FRANCESCA, PRISCO, MARCO
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760688/
https://ncbi.nlm.nih.gov/pubmed/17620314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21185
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