Loading...

Yap1 is dispensable for self‐renewal but required for proper differentiation of mouse embryonic stem (ES) cells

Yap1 is a transcriptional co‐activator of the Hippo pathway. The importance of Yap1 in early cell fate decision during embryogenesis has been well established, though its role in embryonic stem (ES) cells remains elusive. Here, we report that Yap1 plays crucial roles in normal differentiation rather...

Full description

Saved in:
Bibliographic Details
Published in:EMBO Rep
Main Authors: Chung, HaeWon, Lee, Bum‐Kyu, Uprety, Nadima, Shen, Wenwen, Lee, Jiwoon, Kim, Jonghwan
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818770/
https://ncbi.nlm.nih.gov/pubmed/26917425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540933
Tags: Add Tag
No Tags, Be the first to tag this record!