Yap1 is dispensable for self‐renewal but required for proper differentiation of mouse embryonic stem (ES) cells

Yap1 is a transcriptional co‐activator of the Hippo pathway. The importance of Yap1 in early cell fate decision during embryogenesis has been well established, though its role in embryonic stem (ES) cells remains elusive. Here, we report that Yap1 plays crucial roles in normal differentiation rather...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Chung, HaeWon, Lee, Bum‐Kyu, Uprety, Nadima, Shen, Wenwen, Lee, Jiwoon, Kim, Jonghwan
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818770/
https://ncbi.nlm.nih.gov/pubmed/26917425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540933
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