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Insulin Receptor Substrate (IRS)-1 Regulates Murine Embryonic Stem (mES) Cells Self-Renewal
Mouse embryonic stem (mES) cells are pluripotent cells that can be propagated in vitro with leukemia inhibitory factor (LIF) and serum. Intracellular signaling by LIF is principally mediated by activation of STAT-3, although additional pathways for self-renewal have been described. Here, we identifi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760688/ https://ncbi.nlm.nih.gov/pubmed/17620314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21185 |
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