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Insulin Receptor Substrate (IRS)-1 Regulates Murine Embryonic Stem (mES) Cells Self-Renewal

Mouse embryonic stem (mES) cells are pluripotent cells that can be propagated in vitro with leukemia inhibitory factor (LIF) and serum. Intracellular signaling by LIF is principally mediated by activation of STAT-3, although additional pathways for self-renewal have been described. Here, we identifi...

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Bibliografiska uppgifter
Huvudupphovsmän: RUBIN, RAPHAEL, ARZUMANYAN, ALLA, SOLIERA, ANGELA RACHELE, ROSS, BRIAN, PERUZZI, FRANCESCA, PRISCO, MARCO
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760688/
https://ncbi.nlm.nih.gov/pubmed/17620314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21185
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