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Insulin Receptor Substrate (IRS)-1 Regulates Murine Embryonic Stem (mES) Cells Self-Renewal

Mouse embryonic stem (mES) cells are pluripotent cells that can be propagated in vitro with leukemia inhibitory factor (LIF) and serum. Intracellular signaling by LIF is principally mediated by activation of STAT-3, although additional pathways for self-renewal have been described. Here, we identifi...

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Bibliografiset tiedot
Päätekijät: RUBIN, RAPHAEL, ARZUMANYAN, ALLA, SOLIERA, ANGELA RACHELE, ROSS, BRIAN, PERUZZI, FRANCESCA, PRISCO, MARCO
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760688/
https://ncbi.nlm.nih.gov/pubmed/17620314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21185
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