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L1 mobile element expression causes multiple types of toxicity
LINE-1 (L1) retrotransposons represent one of the most successful families of autonomous retroelements, accounting for at least 17% of the human genome. The expression of these elements can be deleterious to a cell. L1 expression has been shown to result in insertional mutagenesis, genomic deletions...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760205/ https://ncbi.nlm.nih.gov/pubmed/18555620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.04.013 |
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