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Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics

BACKGROUND: Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to cells, generating numerous double strand breaks (DSBs). Cells have been report...

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Detalhes bibliográficos
Main Authors: Wallace, Nicholas A, Belancio, Victoria P, Faber, Zach, Deininger, Prescott
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164224/
https://ncbi.nlm.nih.gov/pubmed/20979631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-1-22
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