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Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

Prolonged antibiotic treatment can lead to detrimental side effects in patients, including ototoxicity, nephrotoxicity, and tendinopathy, yet the mechanisms underlying the effects of antibiotics in mammalian systems remain unclear. It has been suggested that bactericidal antibiotics induce the forma...

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Detalhes bibliográficos
Main Authors: Kalghatgi, Sameer, Spina, Catherine S., Costello, James C., Liesa, Marc, Morones-Ramirez, J Ruben, Slomovic, Shimyn, Molina, Anthony, Shirihai, Orian S., Collins, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760005/
https://ncbi.nlm.nih.gov/pubmed/23825301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006055
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