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Reporter Protein Complementation Imaging Assay to Screen and Study Nrf2 Activators in Cells and Living Animals

NF-E2-related factor-2 (Nrf2) activators promote cellular defense mechanism and facilitate disease prevention associated with oxidative stress. In the present study, Nrf2 activators were identified using cell-based luciferase enzyme fragment complementation (EFC) assay, and the mechanism of Nrf2 act...

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Bibliografische gegevens
Hoofdauteurs: Ramkumar, Kunka Mohanram, Sekar, Thillai Veerapazham, Foygel, Kira, Elango, Bhakkiyalakshmi, Paulmurugan, Ramasamy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759980/
https://ncbi.nlm.nih.gov/pubmed/23826874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac401569j
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