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Endogenous Protease Nexin-1 Protects against Cerebral Ischemia

The serine protease thrombin plays a role in signalling ischemic neuronal death in the brain. Paradoxically, endogenous neuroprotective mechanisms can be triggered by preconditioning with thrombin (thrombin preconditioning, TPC), leading to tolerance to cerebral ischemia. Here we studied the role of...

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Autors principals: Mirante, Osvaldo, Price, Melanie, Puentes, Wilfredo, Castillo, Ximena, Benakis, Corinne, Thevenet, Jonathan, Monard, Denis, Hirt, Lorenz
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759934/
https://ncbi.nlm.nih.gov/pubmed/23949634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816719
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