Endogenous Protease Nexin-1 Protects against Cerebral Ischemia

The serine protease thrombin plays a role in signalling ischemic neuronal death in the brain. Paradoxically, endogenous neuroprotective mechanisms can be triggered by preconditioning with thrombin (thrombin preconditioning, TPC), leading to tolerance to cerebral ischemia. Here we studied the role of...

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Bibliografiske detaljer
Main Authors: Mirante, Osvaldo, Price, Melanie, Puentes, Wilfredo, Castillo, Ximena, Benakis, Corinne, Thevenet, Jonathan, Monard, Denis, Hirt, Lorenz
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759934/
https://ncbi.nlm.nih.gov/pubmed/23949634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816719
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