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Endogenous Protease Nexin-1 Protects against Cerebral Ischemia

The serine protease thrombin plays a role in signalling ischemic neuronal death in the brain. Paradoxically, endogenous neuroprotective mechanisms can be triggered by preconditioning with thrombin (thrombin preconditioning, TPC), leading to tolerance to cerebral ischemia. Here we studied the role of...

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Detalhes bibliográficos
Main Authors: Mirante, Osvaldo, Price, Melanie, Puentes, Wilfredo, Castillo, Ximena, Benakis, Corinne, Thevenet, Jonathan, Monard, Denis, Hirt, Lorenz
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759934/
https://ncbi.nlm.nih.gov/pubmed/23949634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816719
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