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Fluorocurcumins as Cyclooxygenase-2 Inhibitor: Molecular Docking, Pharmacokinetics and Tissue Distribution in Mice

PURPOSE: The purpose of the current study was to assess the effect of newly synthesized Curcumin analogs on COX-2 protein by molecular docking studies and by assessments of the effect of one such analog (CDF) on nuclear factor NF-κB and PGE(2). In addition, we have determined the pharmacokinetics an...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Padhye, Subhash, Banerjee, Sanjeev, Chavan, Deepak, Pandye, Shubhangini, Swamy, K.Venkateswara, Ali, Shadan, Li, Jing, Dou, Q. Ping, Sarkar, Fazlul H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759818/
https://ncbi.nlm.nih.gov/pubmed/19714451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9955-6
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