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Fluorocurcumins as Cyclooxygenase-2 Inhibitor: Molecular Docking, Pharmacokinetics and Tissue Distribution in Mice
PURPOSE: The purpose of the current study was to assess the effect of newly synthesized Curcumin analogs on COX-2 protein by molecular docking studies and by assessments of the effect of one such analog (CDF) on nuclear factor NF-κB and PGE(2). In addition, we have determined the pharmacokinetics an...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759818/ https://ncbi.nlm.nih.gov/pubmed/19714451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9955-6 |
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