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Concurrent Inhibition of NF-κB, Cyclooxygenase-2, and Epidermal Growth Factor Receptor Leads to Greater Anti-Tumor Activity in Pancreatic Cancer
Inactivation of survival pathways such as NF-κB, cyclooxygenase (COX-2), or epidermal growth factor receptor (EGFR) signaling individually may not be sufficient for the treatment of advanced pancreatic cancer (PC) as suggested by recent clinical trials. 3,3′-Diindolylmethane (B-DIM) is an inhibitor...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093967/ https://ncbi.nlm.nih.gov/pubmed/20213764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22523 |
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