Concurrent Inhibition of NF-κB, Cyclooxygenase-2, and Epidermal Growth Factor Receptor Leads to Greater Anti-Tumor Activity in Pancreatic Cancer

Inactivation of survival pathways such as NF-κB, cyclooxygenase (COX-2), or epidermal growth factor receptor (EGFR) signaling individually may not be sufficient for the treatment of advanced pancreatic cancer (PC) as suggested by recent clinical trials. 3,3′-Diindolylmethane (B-DIM) is an inhibitor...

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Hlavní autoři: Ali, Shadan, Banerjee, Sanjeev, Schaffert, Jacqueline M., El-Rayes, Bassel F., Philip, Philip A., Sarkar, Fazlul H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093967/
https://ncbi.nlm.nih.gov/pubmed/20213764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22523
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