AMA recognition and structural integrity of the inner lipoyl domain of the E2 subunit of pyruvate dehydrogenase complex (PDC-E2)()

Antimitochondrial autoantibodies (AMA), the serological hallmark of primary biliary cirrhosis (PBC) are directed against the lipoyl domain of the E2 subunit of pyruvate dehydrogenase (PDC-E2). However, comprehensive analysis of the amino acid residues of PDC-E2 lipoyl beta sheet with AMA specificity...

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Detalhes bibliográficos
Main Authors: Wang, Jinjun, Budamagunta, Madhu S., Voss, John C., Kurth, Mark J., Lam, Kit S., Lu, Ling, Kenny, Thomas P., Bowlus, Christopher, Kikuchi, Kentaro, Coppel, Ross L., Ansari, Aftab A., Gershwin, M. Eric, Leung, Patrick S.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759514/
https://ncbi.nlm.nih.gov/pubmed/23894195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301092
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