AMA recognition and structural integrity of the inner lipoyl domain of the E2 subunit of pyruvate dehydrogenase complex (PDC-E2)()

Antimitochondrial autoantibodies (AMA), the serological hallmark of primary biliary cirrhosis (PBC) are directed against the lipoyl domain of the E2 subunit of pyruvate dehydrogenase (PDC-E2). However, comprehensive analysis of the amino acid residues of PDC-E2 lipoyl beta sheet with AMA specificity...

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Hlavní autoři: Wang, Jinjun, Budamagunta, Madhu S., Voss, John C., Kurth, Mark J., Lam, Kit S., Lu, Ling, Kenny, Thomas P., Bowlus, Christopher, Kikuchi, Kentaro, Coppel, Ross L., Ansari, Aftab A., Gershwin, M. Eric, Leung, Patrick S.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759514/
https://ncbi.nlm.nih.gov/pubmed/23894195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301092
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