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Topical delivery of anti-TNFα siRNA and capsaicin via novel lipid-polymer hybrid nanoparticles efficiently inhibits skin inflammation in vivo

The barrier properties of the skin pose a significant but not insurmountable obstacle for development of new effective anti-inflammatory therapies. The objective of this study was to design and evaluate therapeutic efficacy of anti-nociception agent Capsaicin (Cap) and anti-TNFα siRNA (siTNFα) encap...

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Detalhes bibliográficos
Main Authors: Desai, Pinaki R., Marepally, Srujan, Patel, Apurva R., Voshavar, Chandrashekhar, Chaudhuri, Arabinda, Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759511/
https://ncbi.nlm.nih.gov/pubmed/23643662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.04.021
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