Nalaganje...
Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation
Carriers of BRCA1 germline mutations are predisposed to breast and ovarian cancers. Accumulated evidence shows that BRCA1 is quickly recruited to DNA lesions and plays an important role in the DNA damage response. However, the mechanism by which BRCA1 is recruited to DNA damage sites remains elusive...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759356/ https://ncbi.nlm.nih.gov/pubmed/23680151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.03.025 |
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