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Coenzyme depletion by members of the aerolysin family of pore-forming toxins leads to diminished ATP levels and cell death
Recent studies demonstrated that a variety of bacterial pore-forming toxins induce cell death through a process of programmed necrosis characterized by the rapid depletion of cellular ATP. However, events leading to the necrosis and depletion of ATP are not thoroughly understood. We demonstrate that...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759351/ https://ncbi.nlm.nih.gov/pubmed/22688384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25142f |
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