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Toll-like Receptor agonists and alpha-galactosylceramide synergistically enhance the production of interferon-gamma in murine splenocytes

Vα14 natural killer T (iNKT) cells activated by alpha-galactosylceramide (GalCer) secrete a large amount of cytokines. Toll-like receptors (TLRs) play a critical role in the innate immune responses via the recognition of pathological antigen. Previously we demonstrated that the iNKT cells activated...

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Autori principali: Ando, Tatsuya, Ito, Hiroyasu, Ohtaki, Hirofumi, Seishima, Mitsuru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759050/
https://ncbi.nlm.nih.gov/pubmed/23994875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02559
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