Cross-talk between Notch and Hedgehog Regulates Hepatic Stellate Cell Fate

Liver repair involves phenotypic changes in hepatic stellate cells (HSC) and re-activation of morphogenic signaling pathways that modulate epithelial-to-mesenchymal/mesenchymal-to-epithelial transitions, such as Notch and Hedgehog (Hh). Hh stimulates HSC to become myofibroblasts (MF). Recent lineage...

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Autori principali: Xie, Guanhua, Karaca, Gamze, Swiderska-Syn, Marzena, Michelotti, Gregory A., Krüger, Leandi, Chen, Yuping, Premont, Richard T., Choi, Steve S., Diehl, Anna Mae
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758784/
https://ncbi.nlm.nih.gov/pubmed/23703657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26511
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