Expression of GABA Signaling Molecules KCC2, NKCC1, and GAD1 in Cortical Development and Schizophrenia

GABA signaling molecules are critical for both human brain development and the pathophysiology of schizophrenia. We examined the expression of transcripts derived from three genes related to GABA signaling [GAD1 (GAD67 and GAD25), SLC12A2 (NKCC1), and SLC12A5 (KCC2)] in the prefrontal cortex (PFC) a...

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Autori principali: Hyde, Thomas M., Lipska, Barbara K., Ali, Towhid, Mathew, Shiny V., Law, Amanda J., Metitiri, Ochuko E., Straub, Richard E., Ye, Tianzhang, Colantuoni, Carlo, Herman, Mary M., Bigelow, Llewellyn B., Weinberger, Daniel R., Kleinman, Joel E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758549/
https://ncbi.nlm.nih.gov/pubmed/21795557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1234-11.2011
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