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NKCC1 and KCC2 Prevent Hyperexcitability in the Mouse Hippocampus
During postnatal development of the central nervous system (CNS), the response of GABA(A) receptors to its agonist undergoes maturation from depolarizing to hyperpolarizing. This switch in polarity is due to the developmental decrease of the intracellular Cl(−) concentration in neurons. Here we show...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394664/ https://ncbi.nlm.nih.gov/pubmed/18394864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2008.02.005 |
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