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Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery

Targeting therapeutic gene expression to skeletal muscle following intravenous administration is an attractive strategy for treating peripheral arterial disease (PAD), except that vector access to the ischemic limb could be a limiting factor. Since AAV serotype 9 transduces skeletal muscle at high e...

詳細記述

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書誌詳細
主要な著者: Katwal, Arabindra B., Konkalmatt, Prasad R., Piras, Bryan A., Hazarika, Surovi, Li, Sean S., Lye, R. John, Sanders, John M., Ferrante, Elisa A., Yan, Zhen, Annex, Brian H., French, Brent A.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758463/
https://ncbi.nlm.nih.gov/pubmed/23535898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.16
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