Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery

Targeting therapeutic gene expression to skeletal muscle following intravenous administration is an attractive strategy for treating peripheral arterial disease (PAD), except that vector access to the ischemic limb could be a limiting factor. Since AAV serotype 9 transduces skeletal muscle at high e...

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Bibliografiske detaljer
Main Authors: Katwal, Arabindra B., Konkalmatt, Prasad R., Piras, Bryan A., Hazarika, Surovi, Li, Sean S., Lye, R. John, Sanders, John M., Ferrante, Elisa A., Yan, Zhen, Annex, Brian H., French, Brent A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758463/
https://ncbi.nlm.nih.gov/pubmed/23535898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.16
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