Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery

Targeting therapeutic gene expression to skeletal muscle following intravenous administration is an attractive strategy for treating peripheral arterial disease (PAD), except that vector access to the ischemic limb could be a limiting factor. Since AAV serotype 9 transduces skeletal muscle at high e...

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Detalhes bibliográficos
Main Authors: Katwal, Arabindra B., Konkalmatt, Prasad R., Piras, Bryan A., Hazarika, Surovi, Li, Sean S., Lye, R. John, Sanders, John M., Ferrante, Elisa A., Yan, Zhen, Annex, Brian H., French, Brent A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758463/
https://ncbi.nlm.nih.gov/pubmed/23535898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.16
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