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Analysis of Gender Differences in Genetic Risk: Association of TNFAIP3 Polymorphism with Male Childhood-Onset Systemic Lupus Erythematosus in the Japanese Population

BACKGROUND: Systemic lupus erythematosus (SLE) is a systemic multisystem autoimmune disorder influenced by genetic background and environmental factors. Our aim here was to replicate findings of associations between 7 of the implicated single nucleotide polymorphisms (SNPs) in IRF5, BLK, STAT4, TNFA...

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Hlavní autoři: Kadota, Keisuke, Mori, Masaaki, Yanagimachi, Masakatsu, Miyamae, Takako, Hara, Takuma, Kanetaka, Taichi, Nozawa, Tomo, Kikuchi, Masako, Hara, Ryoki, Imagawa, Tomoyuki, Kaneko, Tetsuji, Yokota, Shumpei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758304/
https://ncbi.nlm.nih.gov/pubmed/24023622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072551
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