PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis

OBJECTIVE: Both genetic and environmental factors are associated with susceptibility to juvenile idiopathic arthritis (JIA). Many studies have reported that both a ‘shared epitope’ (SE) encoded by several HLA-DRB1 alleles and the peptidyl arginine deiminase type 4 (PADI4) gene polymorphisms are asso...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hisa, Kaori, Yanagimachi, Masakatsu D., Naruto, Takuya, Miyamae, Takako, Kikuchi, Masako, Hara, Rhoki, Imagawa, Tomoyuki, Yokota, Shumpei, Mori, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300194/
https://ncbi.nlm.nih.gov/pubmed/28182665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171961
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