Fibronectin type III domains engineered to bind CD40L: cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of two complexes

Tn3 proteins are a novel class of binding molecules based on the third fibronectin type III domain of human tenascin C. Target-specific Tn3 proteins are selected from combinatorial libraries in which three surface-exposed loops have been diversified. Here, the cocrystallization of two different Tn3...

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Hlavní autoři: Oganesyan, Vaheh, Ferguson, Andrew, Grinberg, Luba, Wang, Lin, Phipps, Sandrina, Chacko, Benoy, Drabic, Stacey, Thisted, Thomas, Baca, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2013
Témata:
Crystallization Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758160/
https://ncbi.nlm.nih.gov/pubmed/23989160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113022847
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