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Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans

With increasingly large immunocompromised populations around the world, opportunistic fungal pathogens such as Cryptococcus neoformans are a growing cause of morbidity and mortality. To combat the paucity of antifungal compounds, new drug targets must be investigated. Adenylosuccinate synthetase is...

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Detalhes bibliográficos
Main Authors: Blundell, Ross D., Williams, Simon J., Morrow, Carl A., Ericsson, Daniel J., Kobe, Bostjan, Fraser, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758157/
https://ncbi.nlm.nih.gov/pubmed/23989157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113021921
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