Characterization of the Complete Uric Acid Degradation Pathway in the Fungal Pathogen Cryptococcus neoformans

Degradation of purines to uric acid is generally conserved among organisms, however, the end product of uric acid degradation varies from species to species depending on the presence of active catabolic enzymes. In humans, most higher primates and birds, the urate oxidase gene is non-functional and...

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Main Authors: Lee, I. Russel, Yang, Liting, Sebetso, Gaseene, Allen, Rebecca, Doan, Thi H. N., Blundell, Ross, Lui, Edmund Y. L., Morrow, Carl A., Fraser, James A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646786/
https://ncbi.nlm.nih.gov/pubmed/23667704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064292
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