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Expression, purification and crystallization of the ancestral androgen receptor–DHT complex
Steroid receptors (SRs) are a closely related family of ligand-dependent nuclear receptors that mediate the transcription of genes critical for development, reproduction and immunity. SR dysregulation has been implicated in cancer, inflammatory diseases and metabolic disorders. SRs bind their cognat...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758146/ https://ncbi.nlm.nih.gov/pubmed/23989146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113018745 |
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