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Targeted estrogen delivery reverses the metabolic syndrome
We report the development of a new combinatorial approach that allows for peptide-mediated selective tissue targeting of nuclear hormone pharmacology while eliminating adverse effects in other tissues. Specifically, we report the development of a glucagon-like peptide-1 (GLP-1)-estrogen conjugate th...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757949/ https://ncbi.nlm.nih.gov/pubmed/23142820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3009 |
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