Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins

Members of the Cbl protein family (Cbl, Cbl-b, and Cbl-c) are E3 ubiquitin ligases that have emerged as critical negative regulators of protein tyrosine kinase (PTK) signaling. This function reflects their ability to directly interact with activated PTKs and to target them as well as their associate...

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Bibliografiske detaljer
Main Authors: Nadeau, Scott, An, Wei, Palermo, Nick, Feng, Dan, Ahmad, Gulzar, Dong, Lin, Borgstahl, Gloria E. O., Natarajan, Amarnath, Naramura, Mayumi, Band, Vimla, Band, Hamid
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757940/
https://ncbi.nlm.nih.gov/pubmed/23997989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-1009.S6-001
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