Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins

Members of the Cbl protein family (Cbl, Cbl-b, and Cbl-c) are E3 ubiquitin ligases that have emerged as critical negative regulators of protein tyrosine kinase (PTK) signaling. This function reflects their ability to directly interact with activated PTKs and to target them as well as their associate...

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Autori principali: Nadeau, Scott, An, Wei, Palermo, Nick, Feng, Dan, Ahmad, Gulzar, Dong, Lin, Borgstahl, Gloria E. O., Natarajan, Amarnath, Naramura, Mayumi, Band, Vimla, Band, Hamid
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757940/
https://ncbi.nlm.nih.gov/pubmed/23997989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-1009.S6-001
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