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Pharmacokinetics of single-dose primaquine in patients with chronic kidney dysfunction
AIM: The pharmacokinetics of primaquine has not been studied in special populations. Being a basic compound, preferential binding to alpha-1 acid glycoprotein and substrate for P-glycoprotein, may predispose the drug for an altered pharmacokinetics in states of renal dysfunction. This study attempts...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Medknow Publications & Media Pvt Ltd
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757598/ https://ncbi.nlm.nih.gov/pubmed/24014905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.114997 |
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