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Pharmacokinetics of single-dose primaquine in patients with chronic kidney dysfunction

AIM: The pharmacokinetics of primaquine has not been studied in special populations. Being a basic compound, preferential binding to alpha-1 acid glycoprotein and substrate for P-glycoprotein, may predispose the drug for an altered pharmacokinetics in states of renal dysfunction. This study attempts...

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Detalhes bibliográficos
Main Authors: Kulkarni, Shaunak P., Shah, Sanjana R., Kadam, Prashant P., Sridharan, Kannan, Hase, Nivrutti K., Shetty, Partha P., Thatte, Urmila M., Gogtay, Nithya J.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757598/
https://ncbi.nlm.nih.gov/pubmed/24014905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.114997
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