Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia

The response of Philadelphia chromosome (Ph(+)) acute lymphoblastic leukemia (ALL) to treatment by BCR-ABL tyrosine kinase inhibitors (TKIs) has been disappointing, often resulting in short remissions typified by rapid outgrowth of drug-resistant clones. Therefore, new treatments are needed to impro...

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Bibliografski detalji
Glavni autori: Koss, Brian, Morrison, Jeffrey, Perciavalle, Rhonda M., Singh, Harpreet, Rehg, Jerold E., Williams, Richard T., Opferman, Joseph T.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Lymphoid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757371/
https://ncbi.nlm.nih.gov/pubmed/23881917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-440230
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