PHOSPHODIESTERASE 3A EXPRESSION IS MODULATED BY NITRIC OXIDE IN RAT PULMONARY ARTERY SMOOTH MUSCLE CELLS

Phosphodiesterases (PDEs) limit vasodilation in response to a variety of signaling cascades by metabolizing the cyclic nucleotides cAMP and cGMP. The objective of this study was to test the hypothesis that NO regulates expression of PDE3A, a cGMP-inhibited PDE. Incubation of rat pulmonary artery smo...

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Auteurs principaux: BUSCH, C.J., GRAVELINE, A.R., JIRAMONGKOLCHAI, K., LIU, H., SANCHEZ, L.S., BLOCH, K.D.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757338/
https://ncbi.nlm.nih.gov/pubmed/21224496
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