Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes

BACKGROUND: Human embryonic stem cells (hESCs) can be efficiently and reproducibly directed into cardiomyocytes (CMs) using stage-specific induction protocols. However, their functional properties and suitability for clinical and other applications have not been evaluated. METHODS AND RESULTS: Here...

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Main Authors: Lieu, Deborah K., Fu, Ji-Dong, Chiamvimonvat, Nipavan, Chan Tung, Kelvin W., McNerney, Gregory P., Huser, Thomas, Keller, Gordon, Kong, Chi-Wing, Li, Ronald A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757253/
https://ncbi.nlm.nih.gov/pubmed/23392582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.111.973420
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