Facilitated maturation of Ca(2+) handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression

Cardiomyocytes (CMs) are nonregenerative. Self-renewable pluripotent human embryonic stem cells (hESCs) can differentiate into CMs for cell-based therapies. We recently reported that Ca(2+) handling, crucial to excitation-contraction coupling of hESC-derived CMs (hESC-CMs), is functional but immatur...

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Autors principals: Liu, Jing, Lieu, Deborah K., Siu, Chung Wah, Fu, Ji-Dong, Tse, Hung-Fat, Li, Ronald A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Growth, Differentiation, and Apoptosis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711646/
https://ncbi.nlm.nih.gov/pubmed/19357236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00060.2009
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