Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia

An attractive strategy among adenovirus-based oncolytic systems is to design adenoviral vectors to express pro-apoptotic genes, in which this gene-virotherapy approach significantly enhances tumor cell death by activating apoptotic pathways. However, the existence of cancer cells with apoptotic defe...

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Autores principales: Tong, Yin, You, Liangshun, Liu, Hui, Li, Lu, Meng, Haitao, Qian, Qijun, Qian, Wenbin
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2013
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757243/
https://ncbi.nlm.nih.gov/pubmed/23765161
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