MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells

Abnormal proliferation and phenotypic modulation of pulmonary artery smooth muscle cells (PASMC) contributes to the pathogenesis of numerous cardiovascular disorders, including pulmonary arterial hypertension (PAH). The nuclear factor of activated T cells (NFAT) signaling pathway is linked to PASMC...

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Hlavní autoři: Kang, Kang, Peng, Xiao, Zhang, Xiaoying, Wang, Yuna, Zhang, Lishu, Gao, Li, Weng, Tingting, Zhang, Honghao, Ramchandran, Ramaswamy, Raj, J. Usha, Gou, Deming, Liu, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757204/
https://ncbi.nlm.nih.gov/pubmed/23853098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460287
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