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Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude long-term hypoxia: role of histone acetylation

High-altitude long-term hypoxia (LTH) is known to induce pulmonary arterial smooth muscle cell (PASMC) proliferation in the fetus, leading to pulmonary arterial remodeling and pulmonary hypertension of the newborn. The mechanisms underlying these conditions remain enigmatic however. We hypothesized...

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Bibliografski detalji
Glavni autori: Yang, Qiwei, Lu, Ziyan, Ramchandran, Ramaswamy, Longo, Lawrence D., Raj, J. Usha
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532524/
https://ncbi.nlm.nih.gov/pubmed/23043075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00092.2012
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