Pericentric Heterochromatin Generated by HP1 Protein Interaction-defective Histone Methyltransferase Suv39h1

Pericentric regions form epigenetically organized silent heterochromatin structures that accumulate histone H3 lysine 9 trimethylation (H3K9me3) and HP1. At pericentric regions, Suv39h is the major enzyme that generates H3K9me3. Suv39h also interacts directly with HP1, a methylated H3K9-binding prot...

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Bibliografski detalji
Glavni autori: Muramatsu, Daisuke, Singh, Prim B., Kimura, Hiroshi, Tachibana, Makoto, Shinkai, Yoichi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
DNA and Chromosomes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757193/
https://ncbi.nlm.nih.gov/pubmed/23836914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470724
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