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Rho GTPase–independent regulation of mitotic progression by the RhoGEF Net1

Neuroepithelial transforming gene 1 (Net1) is a RhoA-subfamily–specific guanine nucleotide exchange factor that is overexpressed in multiple human cancers and is required for proliferation. Molecular mechanisms underlying its role in cell proliferation are unknown. Here we show that overexpression o...

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Autors principals: Menon, Sarita, Oh, Wonkyung, Carr, Heather S., Frost, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756918/
https://ncbi.nlm.nih.gov/pubmed/23864709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-01-0061
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