UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum

Protein folding in the endoplasmic reticulum (ER) is error prone, and ER quality control (ERQC) processes ensure that only correctly folded proteins are exported from the ER. Glycoproteins can be retained in the ER by ERQC, and this retention contributes to multiple human diseases, termed ER storage...

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Hlavní autoři: Ferris, Sean P., Jaber, Nikita S., Molinari, Maurizio, Arvan, Peter, Kaufman, Randal J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756913/
https://ncbi.nlm.nih.gov/pubmed/23864712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-02-0101
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