Hypothesis: Targeted Ikkβ deletion upregulates MIF signaling responsiveness and MHC class II expression in mouse hepatocytes

Macrophage migration inhibitory factor (MIF) is causally related to the pathogenesis of chronic liver disease but its hepatocellular mechanisms of action are largely unknown. Scattered reports in the literature hint at functional connections between the expression of MIF and major histocompatibility...

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Bibliographic Details
Main Authors: Koch, Katherine S, Leffert, Hyam L
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2010
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Perspectives
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756905/
https://ncbi.nlm.nih.gov/pubmed/23997575
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