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Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters via Ir-Catalyzed Regio-, Diastereo-, and Enantioselective Allylic Alkylation and Applications in Sequential Pd-Catalysis

Highly congested vicinal stereocenters comprised of tertiary and all-carbon quaternary centers were generated via Ir-catalyzed asymmetric allylic alkylation of β-ketoesters. These catalytic reactions proceed in excellent yields with a broad scope on either reaction partner, and with outstanding regi...

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Autores principales: Liu, Wen-Bo, Reeves, Corey M., Virgil, Scott C., Stoltz, Brian M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756902/
https://ncbi.nlm.nih.gov/pubmed/23829704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4052075
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